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  • ISSN[Online] : 2643-9875  ||  ISSN[Print] : 2643-9840

Volume 06 Issue 12 December 2023

Correlation between Macronutrient Intakes (Carbohydrate, Protein, Lipid) and Bone Mineral Density in the Elderly
1Inria Astari Zahra, 2Etisa Adi Murbawani, 3Lusiana Batubara
1Medical Faculty of Diponegoro University – Semarang, Indonesia
2Department of Clinical Nutrition, Medical Faculty of Diponegoro University – Semarang, Indonesia
3Department of Medical Biology and Biochemistry, Medical Faculty of Diponegoro University – Semarang, Indonesia
DOI : https://doi.org/10.47191/ijmra/v6-i12-68

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ABSTRACT:

Osteoporosis is a systemic disease that occurs in bone and is characterized by reduced bone mass and simultaneous damage to bone structure. Osteoporosis commonly occurs in the elderly because of the hormonal mechanism that plays a huge role in bone density. Micronutrients such as calcium and vitamin D have long been recognized as important in maintaining bone structure. Meanwhile, the effect of macronutrient intake on bone density remains unclear. Only a few studies have analyzed the correlation between macronutrient intakes and bone mineral density (BMD) in the elderly. Moreover, the primary data regarding the correlation has not been found in Indonesia. This study analyzed the correlation between macronutrient intakes (carbohydrate, protein, and lipid) and BMD in the elderly. This research is an observational analytical study with a cross-sectional design. Thirty-eight elderly women who met the inclusion criteria underwent an interview with 3 x 24-hour food recall, SQ-FFQ, and examination of bone density using the DXA method. Bivariate analysis using Pearson and Spearman tests was then carried out. Carbohydrate intakes and BMD have a significant negative correlation (p= 0.008), while the correlations of both lipid and protein intake with BMD are insignificant (p> 0.05). There is a significant correlation between carbohydrate intake and BMD in the elderly. On the other hand, there is no significant correlation between protein and lipid intake with BMD in the elderly.

KEYWORDS:

Osteoporosis, macronutrient intake, bone mineral density, elderly

REFERENCES
1) NIH Consensus Statement. Osteoporosis Prevention, Diagnosis, and Therapy. Natl Institutes Heal. 2000;17(1):1–45.

2) World Health Organization. Scientific Group on The Assessment of Osteoporosis at Primary Health Care Level. WHO. 2004;May(May 2004):5–7.

3) Kementrian Kesehatan RI. Situasi dan Analisis Lanjut Usia. 2014. p. 8.

4) Kementerian Kesehatan RI. Data dan Kondisi Penyakit Osteoporosis di Indonesia. 2015. p. 2.

5) Wright NC, Looker AC, Saag KG, Curtis JR, Delzell ES, Randall S, et al. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. J Bone Miner Res. 2014;29(11):2520–6.

6) Demontiero O, Vidal C, Duque G. Aging and bone loss: New insights for the clinician. Ther Adv Musculoskelet Dis. 2012;4(2):61–76.

7) Stránský M, Ryšavá L. Nutrition as Prevention and Treatment of Osteoporosis. Physiol Res. 2009;58:7–11.

8) Scholz-Ahrens KE, Schrezenmeir J. Nutrition and osteoporosis prevention. Ernahrungs Umschau. 2004;51(1).

9) Kerstetter JE. Dietary protein and bone: a new approach to an old question 1, 2. Am J Clin Nutr. 2009;1451–2.

10) Surdykowski AK, Kenny AM, Insogna KL, Kerstetter JE. Optimizing bone health in older adults: The importance of dietary protein. Aging health. 2010;6(3):345–57.

11) Hannan MT, Tucker KL, Dawson-Hughes B, Cupples L a, Felson DT, Kiel DP. Effect of dietary protein on bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res. 2000;15(12):2504–12.

12) Longo AB, Ward WE. PUFAs, Bone Mineral Density, and Fragility Fracture: Findings from Human Studies. Adv Nutr An Int Rev J. 2016;7(2):299–312.

13) Brinkworth GD, Wycherley TP, Noakes M, Buckley JD, Clifton PM. Long-term effects of a very low-carbohydrate weight-loss diet and an isocaloric low-fat diet on bone health in obese adults. Nutrition. Elsevier Inc.; 2016;32(9):1033–6.

14) Marjan AQ, Marliyati SA. Hubungan Antara Pola Konsumsi Pangan dan Aktivitas Fisik dengan Kejadian Osteoporosis pada Lansia di Panti Werdha Bogor. Gizi Dan Pangan. 2013;8(2):123–8.

15) Prihatini S, Mahirawati VK, Jahari AB, Sudiman H. Faktor Determinan Risiko Osteoporosis di Tiga Provinsi di Indonesia. Media Litbang Kesehat. 2010;XX(2):91–9.

16) Setyawati B, Julianti ED, Adha D. Faktor yang berhubungan dengan densitas mineral tulang… (Setyawati B, dkk). 2013;5(2):149–56.

17) Limbong EA, Syahrul F. Rasio Resiko Osteoporosis Menurut Indeks Massa Tubuh, Paritas, dan Konsumsi Kafein. Fak Kesehat Masy Unair. 2014;194–204.

18) Larijani B, Moayyeri A, Keshtkar AA, Hossein-nezhad A, Soltani A, Bahrami A, et al. Peak Bone Mass of Iranian Population: The Iranian Multicenter Osteoporosis Study. 2006;9(3).

19) Fatmah. Osteoporosis dan Faktor Risikonya pada Lansia Etnis Jawa. Media Med Indosiana. 2008;43(2):57–67.

20) Hu T, Zao L, Bazzano L. Effects of a 12-month Low-Carbohydrate Diet vs. a Low-Fat Diet on Bone Mineral Density: A Randomized Controlled Trial. Faseb J. 2016;30:1.

21) Bielohuby M, Sawitzky M, Stoehr BJM, Stock P, Menhofer D, Ebensing S, et al. Growth Hormone ( GH ) Resistance in Rats. 2015;152(May 2011):1948–60.

22) Tian L, Yu X. Fat, Sugar, and Bone Health: A Complex Relationship. 2017;

23) Fauziah LN, Fitrianti DY. Hubungan asupan protein, fosfor , dan kalsium dengan kepadatan tulang wanita dewasa awal. 2015;
Volume 06 Issue 12 December 2023

There is an Open Access article, distributed under the term of the Creative Commons Attribution – Non Commercial 4.0 International (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits remixing, adapting and building upon the work for non-commercial use, provided the original work is properly cited.


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